Which condition is characterized by missing teeth and no hair?

Which condition is characterized by missing teeth and no hair?

• A. Gardner's disease
• B. Ectodermal dysplasia
• C. Trisomy 21
• D. Paget's syndrome

Answer: (B)

The condition characterized by missing teeth and no hair is ectodermal dysplasia. Ectodermal dysplasia refers to a group of genetic conditions involving abnormal development of tissues derived from the ectoderm, which includes skin, hair, nails, and teeth. Individuals with this condition typically present with sparse or absent hair, as well as reduced or absent teeth (hypodontia or anodontia). This aligns perfectly with the features stated in the question. Gardner's disease primarily involves the presence of multiple polyps in the colon and various other tumors and does not specifically manifest with both missing teeth and hair loss. Trisomy 21, also known as Down syndrome, is associated with various physical traits and cognitive challenges but is not specifically connected to the absence of teeth or hair. Paget's syndrome, a condition characterized by abnormal bone remodeling, does not involve the ectodermal structures and thus would not lead to the presentations described in the question. Thus, ectodermal dysplasia uniquely fits the defining characteristics of missing teeth and no hair.

The condition characterized by missing teeth and no hair is ectodermal dysplasia. Ectodermal dysplasia refers to a group of genetic conditions involving abnormal development of tissues derived from the ectoderm, which includes skin, hair, nails, and teeth. Individuals with this condition typically present with sparse or absent hair, as well as reduced or absent teeth (hypodontia or anodontia). This aligns perfectly with the features stated in the question.

Gardner's disease primarily involves the presence of multiple polyps in the colon and various other tumors and does not specifically manifest with both missing teeth and hair loss. Trisomy 21, also known as Down syndrome, is associated with various physical traits and cognitive challenges but is not specifically connected to the absence of teeth or hair. Paget's syndrome, a condition characterized by abnormal bone remodeling, does not involve the ectodermal structures and thus would not lead to the presentations described in the question.

Thus, ectodermal dysplasia uniquely fits the defining characteristics of missing teeth and no hair.